Description: | Osteogenesis Imperfecta, (also known as OI), is a rare genetic disorder commonly known as the "brittle bone" disorder characterized by bones that break easily, often from little or no apparent cause. The cause is a gene defect that affects how you make collagen, a protein that helps make bones strong. There are at least four recognized forms of the disorder, representing extreme variation in severity from one individual to another. For example a person may have just a few or as may as several hundred fractures in a lifetime. |